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therefore, they may attack RBCs, inducing membrane structure changes (erythrocyte shrinkage, membrane blebbing, and PS exposure) and, finally, eryptosis
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NADPH oxidase (NOX), lipoxygenase, cyclooxygenase (COX), xanthine oxidase (XO), uncoupled nitric oxide synthases (NOS), cytochrome P450, and mitochondrial respiration are the most common enzymatic causes of ROS in CVD [11]