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We speculate that LNP-encapsulated si-PGC-1α prevents nanoparticle aggregation and nonspecific protein adsorption within the tumor tissue, allowing si-PGC-1α LNP to remain at the tumor site longer than unencapsulated si-PGC-1α

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[DOI] [PubMed] [Google Scholar] 155.Magalhães P.V., Dean O.M., Bush A.I., Copolov D.L., Malhi G.S., Kohlmann K., Jeavons S., Schapkaitz I., Anderson-Hunt M., Berk M