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There was a statistically significant reduction at two sites in the placebo group, namely the right side of the face and the sun-exposed left forearm
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Differences in baseline reproductive and endocrine status may further contribute to this variability, with women presenting diminished ovarian reserve, pathological ovarian aging, endocrine disorders, or pre-existing immune dysregulation potentially exhibiting greater susceptibility to persistent reproductive abnormalities following SARS-CoV-2 infection (76, 78, 81)